The expanded popularity of meat goat production has led to increased interest in reliable methods to synchronize or induce estrus in goats. With this technology, producers are able to more efficiently use complementary techniques for reproductive management, including artificial insemination and embryo transfer, so that genetic material is more easily obtained or transferred domestically and internationally. Issues involving estrus synchronization protocols include the fact that new product development and inclusion of goats and sheep in labeling for products used in synchronization has not coincided with user interest. Goat and sheep producers therefore have been forced to use products in an extra-label manner. For more information, see links below.