Traditional goals of calf-rearing programs have centered on decreasing mortality and weaning to solid feeds as early as practically feasible on farms. Little thought has been given to the possibility that early feeding practices could influence subsequent productivity when these calves grow into lactating cows. Exciting developments in human biomedical research have shown conclusively that both prenatal and postnatal nutrition can influence metabolic characteristics as adults and the likelihood that adults will contract chronic diseases such as diabetes, hypertension, and atherosclerosis. Might early life nutrition of dairy calves also impact metabolism and the capacity to produce milk as adult cows?
The most recent USDA National Animal Health Monitoring System survey reported that preweaning mortality of heifers alive at 48 h of age was 7.9% (USDA, 2007). Although slightly lower than previous survey results, industry-average morbidity and mortality of preweaned dairy calves remains unacceptably high in the United States. Disease agents and environmental stressors interact with nutrition to determine disease susceptibility (Davis and Drackley, 1998). Labor for care and individual feeding of calves before weaning is the major cost of calf production, but nutritional inputs are also more costly during this period. Therefore, nutrition of young calves remains of paramount importance for calf health and profitability of dairy operations.
Conventional calf-rearing systems historically have restricted the amount of milk or milk replacer fed during the first few weeks of life in an effort to encourage solid feed intake and allow early weaning. Over the last several years, demonstrations of the remarkable improvements in growth and feed efficiency that are obtained by feeding greater quantities of milk (Flower and Weary, 2001; Jasper and Weary, 2002; Khan et al., 2007a,b) or milk replacer (Bartlett, 2001; Diaz et al., 2001; Tikofsky et al., 2001; Blome et al., 2003; Brown et al., 2005; Bartlett et al., 2006) have stimulated renewed interest in early calf nutrition. Such systems have been called by various names, including “accelerated early nutrition,” “accelerated growth,” “enhanced nutrition,” “intensified nutrition,” and “biologically appropriate growth.” While interest in these systems has been high, a major limitation in adoption has been the unknown economic benefits of improved early nutrition. To develop a full economic model of the effect of such systems on dairy enterprise profitability, necessary inputs include effects on the following factors: growth rates and cost per unit height or weight increase, subsequent growth after weaning, health, and subsequent milk production. While data continue to accumulate in each of these areas, it is not yet possible to prepare a complete economic assessment. The objective of this paper is to provide an overview of the current state of knowledge on accelerated early nutrition programs and data that show negative or positive biological effects.
The rationale for so-called accelerated feeding is simple to appreciate if one considers nutrient requirements for growth in young calves. Like other animals, calves require nutrients for maintenance and growth. Moreover, like other animals, amounts of nutrients required are not fixed but vary with body weight (BW) and average daily gain (ADG) of BW. The National Research Council (NRC) in its most recent publication of nutrient requirements for dairy cattle (NRC, 2001) established energy requirements for young calves in terms of metabolizable energy (ME). Recent growth experiments at the University of Illinois and Cornell University have provided data to develop modified NRC equations that better predict growth performance by dairy heifer and bull calves under typical U.S. rearing conditions (Table 1).
Table 1. Nutrient requirements and estimated gain:feed for a 50-kg calf fed milk replacer under thermoneutral conditions, using the Cornell-Illinois modifications of NRC (2001) equations (Van Amburgh and Drackley, 2005).
|Rate of gain, kg/d||Dry matter intake, % BW||Me, Mcal/d||CP, g/d||CP, % of diet DM||Estimated gain:feed|
Several important principles can be demonstrated from data in Table 1. First, the amount of milk solids required to meet maintenance ME requirements is not small. The ME requirements for maintenance under thermoneutral conditions are approximately 1.75 Mcal/d for a 100-lb (45 kg) calf. Whole milk contains about 5.37 Mcal ME/kg of solids, which means that a 45-kg calf requires about 325 g of milk solids, or 2.6 kg of whole milk (about 2.5 L) just for maintenance. Because most milk replacers are lower in fat content than whole milk, they have less ME per unit of solids (4.6 to 4.7 Mcal/kg). Consequently, a 45-kg calf requires about 380 g (0.84 lb) of milk replacer (about 3.0 L as fed) for maintenance. Amounts of milk solids consumed above maintenance can be used for growth.
Second, for calves to grow faster, they need to be fed more milk or milk replacer, or, in older calves, they must consume more starter. Calves clearly respond to greater intake of milk or milk replacer with greater BW gains (Huber et al., 1984; Richard et al., 1988; Diaz et al., 2001; Jasper and Weary, 2002; Brown et al., 2005; Bartlett et al., 2006; Khan et al., 2007a,b). Third, the amount of crude protein (CP) required in the calf’s diet as a percentage of dry matter (DM) is very low for maintenance but increases as rate of gain increases. Fourth, CP content of the diet appears to approach a plateau at about 28% of the DM, which is not unlike the CP content of whole milk solids (about 26% on a DM basis). Finally, these relationships highlight the importance of matching dietary protein and energy intakes with the expected growth performance of the calf. For example, feeding twice as much of a conventional milk replacer with 20% CP does not provide enough protein for lean tissue growth, and the surplus energy will be converted to fat. Conversely, feeding a high-protein milk replacer (e.g., 28% CP) designed for “accelerated growth” at conventional feeding rates of 1 to 1.25 lb/d (454 to 568 g/d) provides excess protein to the calves, which cannot be used for additional growth because energy is limiting. In this case, the excess protein will be degraded and the nitrogen excreted in urine.
Requirements discussed to this point assume that calves are in thermoneutral conditions, which means that they do not need to expend energy to maintain body temperature. The thermoneutral zone for calves less than 21 d of age is 59 to 77°F (NRC, 2001). Consequently, calves in the four-state region spend a considerable portion of their time outside of the thermoneutral zone. Above or below this range, calves must expend more energy to maintain body temperature; in hotter temperatures, they will pant and sweat, and in colder temperatures, they will shiver and use other means to increase heat production. This increase in energy expended becomes part of the maintenance energy requirement. For calves older than 21 d, the lower critical temperature falls to about 41°F, which means they are more able to withstand colder temperatures because of increases in body fat content and hair coat. The increased maintenance energy requirement in cold temperatures is built into the NRC model (NRC, 2001). As environmental temperature decreases, maintenance requirements for ME increase. A 100-lb calf at -4°F requires about 563 g/d of milk replacer powder just to meet maintenance requirements and maintain body temperature, compared with about 382 g/d of powder under thermoneutral conditions. If calves are fed the same amount of milk or milk replacer as in thermoneutral conditions, less energy will be available to fuel growth.
Heat stress also increases the maintenance energy requirements of calves, although the exact amount needed for cooling has not been as well quantified as the effects of cold stress. Estimates based on data for older growing cattle (NRC, 2001) would indicate increased maintenance requirements of 20 to 30% (about 0.15 to 0.25 lb more milk replacer powder) during heat stress. Free choice water availability and shade are critical to maintain body temperature in young calves. Sand bedding also helps calves dissipate heat better than straw or wood shavings.
Based on data from an Israeli study (Arieli et al., 1995), an additional maintenance requirement may be needed by young calves undergoing transport. On average, this amount is about 100 g of powder for calves weighing 43 to 50 kg. Calves should be fed this increased amount (in addition to any needed for temperature allowance) for 14 d following transport (Van Amburgh and Drackley, 2005).
Traditionally, calves have been fed limited amounts of milk or milk replacer (typically 8 to 10% of birth BW) with starter offered for ad libitum consumption from the first week of life. This amount of liquid feed is much lower than ad libitum intakes, which are in the range of 16 to 20% of BW or 2 to 2.5% of BW as dry solids (Hafez and Lineweaver, 1968). The restricted liquid feeding approach arose in an attempt to stimulate early intake of starter and to minimize input costs of higher-value feed. In addition, early milk replacers were of poor quality and were not well utilized by calves at higher feeding rates (Davis and Drackley, 1998). Restricted feeding allows only for maintenance requirements and up to about 0.5 lb/d ADG under thermoneutral conditions (Table 1). As starter intake increases, typically doubling every week, enough nutrients are consumed to allow calves to begin to grow rapidly (Kertz et al., 1979).
A contrasting approach is the accelerated feeding system, which allows calves much greater intakes of liquid feed during early life, closer to “natural” conditions in which calves would have ad libitum access to milk. Milk feeding rates are approximately twice those of conventional systems. An easy rule of thumb is to provide 1.5% of BW as milk solids during the first week of life, then 2% of BW from the second week of life until the week before weaning, when one feeding is dropped (Stamey et al., 2005). Intake of starter will lag behind calves fed on conventional systems but increases at approximately the same rate once the amount of liquid is cut back (Stamey et al., 2005; Hill et al., 2006, 2007)]. To avoid or minimize growth slumps around weaning, calves should not be weaned until they are consistently eating 2 lb of starter daily. As shown in Figure 1, the major difference in growth rate is in the first 2 to 3 weeks of life, and after that, growth rates generally are parallel. Accelerated feeding programs using whole milk also can be successful, particularly when implemented with step-down (Khan et al., 2007a,b) or gradual weaning programs (Jasper and Weary, 2002).
Feeding programs have been developed that are intermediate in nature to accelerated and conventional programs. These moderately aggressive programs call for liquid intakes between those in conventional and accelerated programs (Stamey et al., 2006; Hill et al., 2006). These programs are reported to result in less slump in growth around weaning and fewer digestive upsets in calves than more aggressive liquid feeding programs (Hill et al., 2006) while still providing improved nutritional status during the critical first 2 to 3 weeks (Stamey et al., 2006). Milk replacers designed for use in intermediate programs usually contain 24 to 26% CP and are fed at 1.5 to 1.75% of BW. While easier to implement, they do not fully capitalize on the early growth potential. These programs may be more easily implemented with transported or colostrum-deprived calves than are more aggressive accelerated programs (Hill et al., 2006).
Benefits of improved nutritional status in the first 2 to 3 weeks may include reaching breeding age (and thus calving age) sooner, an improved ability to withstand infectious challenges, and increased subsequent milk production (Drackley, 2005).
The increased early growth of heifers easily translates into 2-week earlier calving age if typical BW or height differences at weaning are maintained. If heifers continue to grow more rapidly, the advantage may increase to more than 1 month. Of course, to realize this decrease in calving age, heifers must be bred according to body size rather than age. It is important to note that calves must have adequate early colostrum intake to be able to efficiently use additional nutrients from milk intake. In addition, calves undergoing adaptation to stressors such as transport also may be less able to utilize high amounts of milk solids intake in early life (Hill et al., 2006; Quigley et al., 2006).
Poor health during early life is believed to have long-lasting effects on milk production and herd life. Epidemiological studies relating specific neonatal illnesses to later productivity generally have not found strong relationships between any specific illness or condition and subsequent survivability or productivity, although respiratory disease in calves increased the age at first calving (Correa et al., 1988). Early-life “dullness” in calves was a significant risk factor for shorter herd life. Calves that were characterized as having dullness before 90 d of age (defined as dull appearance, listlessness, droopy ears, and off feed) were 4.3 times more likely to die after 90 d of age (Curtis et al., 1989) and 1.3 times more likely to leave the milking herd than herdmates (Warnick et al., 1997). The authors speculated that this condition might reflect the combined effects of poor health and suboptimal nutrition.
Considerable evidence points to inadequate nutrition during early life as a major factor in decreased resistance to disease and compromised health and well being. Williams et al. (1981) compared calves fed two amounts of milk replacer solids (600 g/d and either 300 or 400 g/d) with either ad libitum or restricted access to calf starter. Calves fed the higher amount of milk replacer with ad libitum access to starter had the greatest ADG and least mortality. More recently, Khan et al. (2007b) showed a reduction in fecal scores for calves fed at an accelerated rate with whole milk.
The available evidence suggests that improvements in health seen with calves fed greater amounts of milk or milk replacer likely are due to improved overall nutritional status rather than to any specific alterations in immune system characteristics or function. Studies that have examined functional aspects of components of the immune system generally have found small differences between calves fed conventionally or on accelerated programs (Griebel et al. 1987; Pollock et al., 1993, 1994; Nonnecke et al. 2003; Foote et al., 2005, 2007). Unfortunately, studies are not available in which calves have been grown on different planes of nutrition and then challenged with a disease organism to assess the impact of plane of nutrition on the ability to prevent disease or recover more quickly from disease.
The health status of young calves is affected by interactions of early nutrition and the environment. Nutritional insufficiency may be especially problematic for immune function during cold or heat stress, when maintenance requirements for temperature regulation are increased. For example, we conducted an experiment to determine the value of supplementing milk replacer with energy sources for Jersey calves raised in hutches during winter (Drackley et al., 1996). To do so required establishment of an appropriate baseline feeding regimen. Jersey heifer calves fed a conventional milk replacer at 8% of BW did not maintain BW and had a high incidence of health problems. Calves fed the same milk replacer at 10% of BW gained small amounts of BW but still were unhealthy. Only when calves were fed at a rate of 12% of BW were they able to maintain health and modest rates of BW gain.
A study conducted in Minnesota (Godden et al., 2005) compared equal volumes of pasteurized non-salable milk and a conventional milk replacer. Because whole milk contains about 17% more energy than milk replacer at equal amounts, indirectly these authors were comparing two planes of nutrition. Calves fed the pasteurized non-salable milk had greater ADG than those fed milk replacer. In summer, mortality of calves did not differ between those fed milk (2.2%) or milk replacer (2.7%). However, for calves born in the winter, mortality was much greater for calves fed milk replacer (21.0%) than for those fed milk (2.8%). Much of this difference is likely attributable to the marginal nutrient status of the calves fed milk replacer because of the greater maintenance energy requirements during cold stress.
One of the most exciting current areas of research concerning accelerated feeding is to document long-term effects of early nutrition on subsequent productivity. As more and more lactation data become available for calves fed differently after birth, it is becoming clear that improved growth rates and early nutrition translate into greater milk production. Several earlier studies suggested improvements in subsequent milk production when calves were fed greater amounts of milk (Foldager and Krohn, 1994; Foldager et al., 1997; Bar-Peled et al., 1997). Average improvements in first-lactation milk yield are in the range of 1,000 to 2,000 lb of milk.
We compared an accelerated milk replacer feeding system with a conventional limit-feeding system for calves born in spring and summer over two subsequent years (Pollard et al., 2003). The same milk replacers were fed in each year, but the feeding rate of the accelerated program varied slightly in the two years; consequently, each year represents a separate trial. Calves fed the accelerated treatments had greater ADG during the milk feeding period (Table 2) but stalled markedly around weaning. By 12 weeks of age, differences in BW and stature had narrowed between groups. First-lactation 305-day actual milk yields (Drackley et al., 2007) are shown in Table 2. Early life enhanced feeding resulted in greater milk production during the first lactation, although the tendency for the diet by trial interaction indicates that the difference was greater for trial 1 than trial 2. “Accelerated” heifers from trial 1 calved about 1 month later on average, were slightly larger, and had greater milk yields. Heifers from both diets in trial 2 calved at the same average age and BW, and milk yields differed less. Regardless of diet, heifers from trial 2 did not perform as well as those from trial 1. This points out the importance of variation from year to year, which complicates on-farm determination of effects of management changes. Correlation analysis revealed that ADG was correlated negatively with subsequent milk production within the conventional treatment but was correlated positively with milk production in the accelerated treatment (M.E. Van Amburgh and J.K. Drackley, unpublished).
Table 2. Growth and first-lactation data for heifers fed either conventional or intensified milk replacer programs as calves in two trials (Drackley et al., 2007).
|ADG to weaning (lb)|
|Age at calvinga (mo)|
|Calving BW (lb)|
|305-d milkabc (mo)|
aTrial, P < 0.01.
bDiet, P < 0.01.
cDiet x trial, P = 0.13.
We currently are completing analysis of a large experiment with heifer and bull calves born on the University of Illinois dairy farm (Stamey et al., 2005, and unpublished). The experiment compared a traditional restricted-feeding program of a 20% CP, 20% fat milk replacer with an intensified step-up feeding program using a 28% CP, 15% fat milk replacer. Both groups of calves had starter and water available free choice and were weaned at 6 weeks of age. The ADG through 8 weeks of age were 20% greater (777 g/d versus 648 g/d) for the intensified calves. Of greater importance is that gains of withers height were also about 24% greater for the intensified calves. We have followed these heifers through subsequent growth and first lactation, and the data should allow a complete economic evaluation of the program.
The concept of “accelerated feeding” for young milk-fed calves is now well accepted as an alternative to traditional restricted feeding. Research and field experience have highlighted many aspects that are important for successful implementation. Calves must be fed a properly formulated milk replacer or whole milk at approximately twice the conventional rate. A step-down or gradual weaning process facilitates a smoother transition to dry feed. Colostrum-deprived calves or calves that are undergoing transport stress will not respond as well to increased amounts of milk and may in fact be affected negatively. Benefits to accelerated milk-feeding programs include decreased age at first calving, improvements in health, and increased milk production. Ongoing research will provide the necessary input variables to model the overall economic impact of accelerated milk feeding programs.
Arieli, A., J.W. Schrama, W. Van Der Hel, and M.W. Verstegen. 1995. Development of metabolic partitioning of energy in young calves. J. Dairy Sci. 78:1154-1162.
Bar-Peled, U., B. Robinzon, E. Maltz, H. Tagari, Y. Folman, I. Bruckental, H. Voet, H. Gacitua, and A.R. Lehrer. 1997. Increased weight gain and effects on production parameters of Holstein heifer calves that were allowed to suckle from birth to six weeks of age. J. Dairy Sci. 80:2523-2528.
Bartlett, K.S. 2001. Interactions of Protein and Energy Supply from Milk Replacers on Growth and Body Composition of Dairy Calves. M.S. Thesis, University of Illinois, Urbana.
Bartlett, K.S., F.K. McKeith, M.J. VandeHaar, G.E. Dahl, and J.K. Drackley. 2006. Growth and body composition of dairy calves fed milk replacers containing different amounts of protein at two feeding rates. J. Anim. Sci. 84:1454-1467.
Blome, R.M., J.K. Drackley, F.K. McKeith, M.F. Hutjens, and G.C. McCoy. 2003. Growth, nutrient utilization, and body composition of dairy calves fed milk replacers containing different amounts of protein. J. Anim. Sci. 81:1641-1655.
Brown E.G., M.J. Vandehaar, K.M. Daniels, J.S. Liesman, L.T. Chapin, D.H. Keisler, and M.S. Nielsen. 2005. Effect of increasing energy and protein intake on body growth and carcass composition of heifer calves. J. Dairy Sci. 88:585-594.
Correa, M.T., C.R. Curtis, H.N. Erb, and M.E. White. 1988. Effect of calfhood morbidity on age at first calving in New York Holstein herds. Prev. Vet. Med. 6:253-262.
Curtis, C.E., M.E. White, and H.N. Erb. 1989. Effects of calfhood morbidity on long-term survival in New York Holstein herds. Prev. Vet. Med. 7:173-186.
Diaz, M.C., M.E. Van Amburgh, J.M. Smith, J.M. Kelsey, and E.L. Hutten. 2001. Composition of growth of Holstein calves fed milk replacer from birth to 105 kilogram body weight. J. Dairy Sci. 84:830-842.
Drackley, J.K. 2005. Early growth effects on subsequent health and performance of dairy heifers. Chapter 12 in Calf and Heifer Rearing. P.C. Garnsworthy, ed. Nottingham University Press, Nottingham, UK.
Drackley, J.K., and M.E. Van Amburgh. 2005. Nutrient requirements of the calf: Birth to weaning. Pages 86-95 in Dairy Calves and Heifers. Integrating Biology and Management. NRAES publ. 175, Cooperative Extension, Ithaca, NY.
Drackley, J.K., B.C. Pollard, H.M. Dann, and J.A. Stamey. 2007. First-lactation milk production for cows fed control or intensified milk replacer programs as calves. J. Dairy Sci. 90(Suppl. 1):614. (Abstr.)
Drackley, J.K., L.D. Ruppert, J.P. Elliott, G.C. McCoy, and E.H. Jaster. 1996. Effects of increased solids in milk replacer on Jersey calves housed in hutches during winter. J. Dairy Sci. 79(Suppl. 1):154. (Abstr.)
Flower, F.C., and D.M. Weary. 2001. Effects of early separation on the dairy cow and calf: 2. Separation at 1 day and 2 weeks after birth. Appl. Anim. Behav. Sci. 70:275-284.
Foldager, J., and Krohn, C.C. 1994. Heifer calves reared on very high or normal levels of whole milk from birth to 68 weeks of age and their subsequent milk production. Proc. Soc. Nutr. Physiol. 3 (Abstr.)
Foldager, J., C.C. Krohn, and L. Mogensen. 1997. Level of milk for female calves affects their milk production in first lactation. In Proc. 48th Ann. Mtg. European Assoc. Anim. Prod.
Foote, M.R., B.J. Nonnecke, D.C. Beitz, and W.R. Waters. 2007. High growth rate fails to enhance adaptive immune responses of neonatal calves and is associated with reduced lymphocyte viability. J. Dairy Sci. 90:404-417.
Foote, M.R., B.J. Nonnecke, W.R. Waters, M.V. Palmer, D.C. Beitz, M.A. Fowler, B.L. Miller, T.E. Johnson, and H.B. Perry. 2005. Effects of increased dietary protein and energy on composition and functional capacities of blood mononuclear cells from vaccinated, neonatal calves. Int. J. Vitam. Nutr. Res. 75:357-368.
Godden, S.M., J.P. Fetrow, J.M. Freitag, L.R. Green, and S.J. Wells. 2005. Economic analysis of feeding pasteurized non-salable milk versus conventional milk replacer to dairy calves. J. Am. Vet. Med. Assoc. 226:1547-1554.
Griebel, P.J., M. Schoonderwoerd, and L.A. Babiuk. 1987. Ontogeny of the immune response: Effect of protein energy malnutrition in neonatal calves. Can. J. Vet. Res. 51:428-435.
Hafez, E.S.E., and L.A. Lineweaver. 1968. Suckling behaviour in natural and artificially fed neonate calves. Z. Tierpsychol. 25:187-198.
Hill, T.M., J.M. Aldrich, R.L. Schlotterbeck, and H.G. Bateman II. 2006. Effects of feeding calves different rates and protein concentrations of 20 percent fat milk replacers on growth during the neonatal period. Prof. Anim. Sci. 22:252-260.
Hill, T.M., H.G. Bateman, II, J.M. Aldrich, and R.L. Schlotterbeck. 2007. Effects of feeding rate of milk replacers and bedding material for calves in a cold, naturally ventilated nursery. Prof. Anim. Sci. 23:656-664.
Huber, J.T., A.G. Silva, O.F. Campos, and C.M. Mathieu. 1984. Influence of feeding different amounts of milk on performance, health, and absorption capability of baby calves. J. Dairy Sci. 67:2957-2963.
Jasper, J., and D.M. Weary. 2002. Effects of ad libitum milk intake on dairy calves. J. Dairy Sci. 85:3054-3058.
Kertz, A.F., L.R. Prewitt, and J.P. Everett, Jr. 1979. An early weaning calf program: Summarization and review. J. Dairy Sci. 62:1835-1843.
Khan, M.A., H.J. Lee, W.S. Lee, H.S. Kim, S.B. Kim, K.S. Ki, J.K. Ha, H.G. Lee, and Y.J. Choi. 2007a. Pre- and post-weaning performance of Holstein female calves fed milk through step-down and conventional methods. J. Dairy Sci. 90:876-885.
Khan, M.A., H.J. Lee, W.S. Lee, H.S. Kim, K.S. Ki, T.Y. Hur, G.H. Suh, S.J. Kang, and Y.J. Choi. 2007b. Structural growth, rumen development, and metabolic and immune responses of Holstein male calves fed milk through step-down and conventional methods. J. Dairy Sci. 90:3376-3387.
National Research Council. 2001. Nutrient Requirements of Dairy Cattle. 7th Rev. Ed. National Academy Press, Washington, DC.
Nonnecke, B.J., M.R. Foote, J.M. Smith, B.A. Pesch, and M.E. Van Amburgh. 2003. Composition and functional capacity of blood mononuclear leukocyte populations from neonatal calves on standard and intensified milk replacer diets. J. Dairy Sci. 86:3592-3604.
Pollard, B.C., H.M. Dann, and J.K. Drackley. 2003. Evaluation of intensified liquid feeding programs for dairy calves. J. Dairy Sci. 86(Suppl. 1):174. (Abstr.)
Pollock, J.M., T.G. Rowan, J.B. Dixon, S.D. Carter, D. Spiller, and H. Warenius. 1993. Alteration of cellular immune responses by nutrition and weaning in calves. Res. Vet. Sci. 55:298-306.
Pollock, J.M., T.G. Rowan, J.B. Dixon, and S.D. Carter. 1994. Level of nutrition and age at weaning: Effects on humoral immunity in young calves. Br. J. Nutr. 71:239-248.
Quigley, J.D., T.A. Wolfe, and T.H. Elsasser. 2006. Effects of additional milk replacer feeding on calf health, growth, and selected blood metabolites in calves. J. Dairy Sci. 89:207-216.
Richard A.L., L.D. Muller, and A.J. Heinrichs. 1988. Ad libitum or twice daily feeding of acidified milk replacer to calves housed individually in warm and cold environments. J. Dairy Sci. 71:2193-2202.
Stamey, J.A., N.A. Janovick Guretzky, and J.K. Drackley. 2005. Influence of starter protein content on growth of dairy calves in an enhanced early nutrition program. J. Dairy Sci. 88(Suppl. 1):254. (Abstr.)
Stamey, J.A., R.L. Wallace, K.R. Grinstead, D.R. Bremmer, and J.K. Drackley. 2006. Influence of plane of nutrition on growth of dairy calves. J. Dairy Sci. 89:1871. (Abstr.)
Tikofsky, J.N., M.E. Van Amburgh, and D.A. Ross. 2001. Effect of varying carbohydrate and fat content of milk replacer on body composition of Holstein bull calves. J. Anim. Sci. 79:2260-2267.
USDA. 2007. Dairy 2007, Part I: Reference of Dairy Cattle Health and Management Practices in the United States, 2007. Fort Collins, CO: USDA-APHIS-VS, CEAH.
Van Amburgh, M., and J. Drackley. 2005. Current perspectives on the energy and protein requirements of the pre-weaned calf. Chapter 5 in Calf and Heifer Rearing. P.C. Garnsworthy, ed. Nottingham University Press, Nottingham, UK.
Warnick, L.D., H.N. Erb, and M.E. White. 1997. The relationship of calfhood morbidity with survival after calving in 25 New York Holstein herds. Prev. Vet. Med. 31:263-273.
Williams, P.E.V., D. Day, A.M. Raven, and J.A. McLean. 1981. The effect of climatic housing and level of nutrition on the performance of calves. Anim. Prod. 32:133-141.
James K. Drackley
Department of Animal Sciences
University of Illinois at Urbana-Champaign
Urbana, IL 61801